A paper utilizing our 16S rRNA Bacterial Flora Analysis was published by Dr. Miyuki Yoshikawa, Dr. Daiki Rokunohe et al., Hirosaki University Graduate School of Medicine, Department of Dermatology. This paper reported on inflammation and bacterial flora in intratarsal keratinous cysts (IKC), which are pigmented intraocular keratinocysts.
IKC, a benign cystic lesion of the eyelid, usually appears as a yellow to white cyst, but rarely as a brown or gray-blue cyst, affecting the clinical diagnosis. The cause of this phenomenon is not known. The author's research group has observed a localized lymphocytic infiltrate in the melanocyte-rich, melanin-positive area below the cyst wall in pigmented IKC, and has analyzed the bacterial colonies within the cyst for the presence of Corynebacterium species. The etiology of pigmented IKC related to inflammation and bacterial flora was discussed in the paper.
We have performed 16S rRNA Bacterial Flora Analysis using the bacterial colonies in the cysts described in the paper.

The Journal of Dermatology
Involvement of the genus Corynebacterium in the pathogenesis of pigmented intratarsal keratinous cyst

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