A paper utilizing our TCR Repertoire Analysis was published by Dr. Hisashi Yano, Shin Kaneko Laboratory, CiRA, Kyoto University.
In this paper, they report a success in producing CD4⁺ Treg-like cells derived from human iPS cells by inducing FOXP3 expression.
Using our TCR Repertoire Analysis, it was confirmed that cells cultured from non-T cell-derived iPS cells reconstitute various TCRα and β genes during their differentiation, constituting a polyclonal TCR repertoire.

Cell Stem Cell
Human iPSC-derived CD4⁺ Treg-like cells engineered with chimeric antigen receptors control GvHD in a xenograft model

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